"Psilocybin: /3-(2-Dimethylaminoethyl)-1H-indol-4-yl/ dihydrogen phosphate"
(C12 H17 N2 O4 P)
How Do Psychedelics Work?
According to Dr. Jerrold Rosenbaum, the director of the newly created Center for the Neuroscience of Psychedelics at Massachusetts General Hospital and former psychiatrist-in-chief at MGH, the short answer is, "Psychedelics induce the brain to change transiently in ways that appear to allow a reset to take place and permit alterations in previously 'stuck' ways of feeling and thinking about things."
There are likely several ways in which psychedelics can accomplish this: new connections are briefly made in neural networks while the resting state of the brain (or the "default mode network") loses connectivity — then it restores itself. "It’s like rebooting your computer."
This is how stuck patterns of thinking are thought to shift. Also, new connections between neurons are formed, a process that is called neuroplasticity. Finally, the psychedelic drugs themselves can put patients into a transient state where they can better process memories, feelings, and past trauma, and can "reemerge with a new perspective on them that is freeing and healing" — also called psychedelic-assisted therapy. - Peter Grinspoon, MD, (Harvard Health)
What is Microdosing?
Microdosing is the act of consuming sub-perceptual (unnoticeable) amounts of a psychedelic substance. Many individuals who have integrated microdosing mushrooms into their weekly routine report higher levels of creativity, more energy, increased focus, and improved relational skills, as well as reduced anxiety, stress, and even depression. Some enthusiasts also report that microdosing mushrooms has helped them heighten their spiritual awareness and enhance their senses.
Psychedelic researchers have also discovered that psilocybin can have positive effects on mood disorders and anxiety. In fact, The Beckley Foundation is spearheading the push for the legalization of psilocybin mushrooms, backed by their research showing that psilocybin has long-term positive effects for treatment-resistant depression patients.
Psilocybin is also proving effective at treating addiction. Researchers from Johns Hopkins found that 80% of smokers who took psilocybin as part of cognitive behavioral therapy were able to quit tobacco completely. Mushrooms have also been found to have comparable or better results in treating cluster headaches than most conventional medications—many people have experienced extended periods of remission after treating their headaches with psychedelic substances.
--With all these encouraging results on full doses of psilocybin, there’s reason to believe that microdosing mushrooms could bring about similarly positive life changes.
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